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Irregular Sleep​-​Wake (Tryptophan)

from Circadian Rhtyhms Sleep Disorders by Marco "uBiK" Bonini

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relative absence of a circadian pattern to the sleep-wake cycle. Total sleep time may be comparatively normal, but instead of being consolidated into distinct bout or bouts, sleep times are shortened, and in extreme cases, almost randomly distributed throughout the day and night. In otherwise healthy people, the condition may be a result of very poor sleep hygiene; commonly associated with neurological impairment, such as mental retardation in children and dementia in older adults.The cause (or more likely, the causes) of this association are unknown, but damage to the circadian pacemaker in the Suprachiamastic Nucleus (SCN) is clearly implicated as an important, if not a major, etiological factor. Indeed, experimental ablation of the SCN in animals produces a loss of circadian rhythmicity that strongly resembles the sleep/wake pattern typically seen in older adults with dementing disorders, particularly in the later stages of the dementia. tryptophan:the amino acid tryptophan is a building block of proteins. it has been claimed to contribute to sleepiness, since it is a precursor of the neurotransmitter serotonin, involved in sleep regulation. however, no solid data have ever linked modest dietary changes in tryptophan to changes in sleep.

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from Circadian Rhtyhms Sleep Disorders, released May 31, 2012

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Marco "uBiK" Bonini Rome, Italy

uBiK is a solo project by Marco Bonini - avant-jazz trained guitarist, inspired by hypnagogic ambient music. His primary source materials are real time processed field recordings and filtered electric guitars using softwares such as Ableton Live and Max/Msp. He uses a wide array of guitar sounds to create a highly textural intense music, taking cues from drone, noise and musique concrete. ... more

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